Pheniramine Maleate belongs to the group of medicines called Antihistamines. It is used in the management of allergic conditions (such as hay fever, angioneurotic edema, drug rashes, serum sickness, allergic conjunctivitis, and food allergy), conditions of the respiratory tract which involve increased secretions (vasomotor rhinitis, acute rhinitis).
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Allergy is a condition in which the immune system reacts abnormally to foreign substances, such as pollen, dust mites, mold spores, food, pet dander, insect stings, and medicines/drugs. The common types of allergies include drug allergy, food allergy, contact dermatitis, latex allergy, allergic asthma, seasonal allergy, animal allergy, and anaphylaxis (severe allergy). Symptoms can range from mild rashes, hives, itching, watery eyes/nose, or runny nose to severe allergic reactions, which could be life-threatening.
Alervil Syrup is used to treat allergic conditions such as hay fever, runny nose, allergic conjunctivitis, vasomotor rhinitis, acute rhinitis, and itching skin conditions. Additionally, Alervil Syrup is also used to prevent and treat motion sickness, nausea, vomiting, and vertigo due to Menière's disease and other labyrinthine disturbances.
You are recommended not to consume alcohol along with Alervil Syrup to avoid unpleasant side effects.
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Alervil Syrup as it is a pregnancy category C drug
Only consume Alervil Syrup if a doctor prescribes you.
Do not drive or operate machinery if you experience drowsiness or difficulty in concentrating while using Alervil Syrup. Alervil Syrup may affect your ability to drive. Seek medical attention if the symptoms persist longer.
Alervil Syrup should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Alervil Syrup
Let your doctor know if you have any history of kidney diseases. Alervil Syrup should be used with caution in patients with liver diseases.
Treatment of Allergic conditions, Motion/travel sickness, and Meniere's disease
It works by blocking the action of a chemical messenger called 'histamine', which is responsible for causing allergic reactions. Thereby Alervil Syrup treats allergic conditions.
Consult your doctor if you experience any unusual symptoms such as agitation and convulsions, especially in children, and hallucinations, restlessness, and disorientation in adults.
Pheniramine works by competing with histamine for the H1 receptor and acts as an inverse agonist once it binds. This action leads to a decrease in H1 receptor activity, which in turn reduces itching, vasodilation, and capillary leakage, ultimately leading to less redness and swelling. This effect is particularly evident in the suppression of the histamine-induced wheal (swelling) and flare (vasodilation) response.
In the central nervous system (CNS), the inverse agonism of the H1 receptor by pheniramine is responsible for the sedative effects commonly associated with first-generation antihistamines. Additionally, pheniramine's binding to H4 receptors and its inverse agonism at these sites may also help reduce itching by counteracting inflammation.
Syrup (15 mg/5 ml): For children aged 1-3 years, half a measuring spoonful 2-3 times daily; for those aged 4-12 years, 1 measuring spoonful 2-3 times daily; for adults and young people, 1-2 measuring spoonfuls twice or three times daily after meals. Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Pregnancy Category C: Use only if the potential benefit justifies the potential risk to the fetus.
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